Takis Benos

Congratulations to Minxue Jia, Khaled Sayed, and Maria Kapetanaki for the acceptance of their joint first author Aging Cell paper, which is entitled “LEF1 isoforms regulate cellular senescence and aging“. In this paper, our group analyzed scRNA-seq data from immune cells from human and mouse lungs (young and aged) and bulk RNA-seq data from human…

 Today, Feng presented elegantly his PhD thesis work during the past 6+ years in Dario Vignali’s lab. I was very lucky to co-advise him and have him participating in our group’s activities. His PhD thesis is entitled “integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells.”  You can…

Takis gave an invited talk and met with colleagues at the National Institute of Drug Abuse (NIDA). The title of the talk was “Going beyond associations: causal modeling in multi-scale medical research”.  …

Congratulations to Tyler Lovelace for the acceptance of his first co-author BMC Medicine paper, which is entitled “Integrated unbiased multiomics defines disease-independent placental clusters in common obstetrical syndromes”. In this paper, Tyler analyzed placental-derived multi-comics datasets (mRNA, miRNA, proteins, metabolites) from pregnant women with different pregnancy abnormalities: preeclampsia, fetal growth restriction, spontaneous preterm…

Congratulations to Robert Gregg for the acceptance of his AJRCCM paper (“Blue journal”), which is entitled “Early Evidence of COPD Obscured by Race-Specific Prediction Equations”. This paper examines the impact of race-specific equations in the determination of the COPD disease status and severity. The main finding is that current race-specific equations underestimate the…

Congratulations to Minxue Jia for the acceptance of his first author Aging Cell paper, which is entitled “Transcriptional Changes of the Aging Lung”. In this paper, Minxue analyzed lung scRNA-seq data from carefully selected healthy donors across life span (19-78 yrs old). Some of the samples were the controls from existing publications, whereas…

Congratulations to Feng Shan for the acceptance of his first author Science Immunology paper, which is entitled “Integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells”. In this paper, Feng analyzes scRNA-seq data to uncover the transcriptional programs that control intratumoral Treg gene expression. This is a collaboration with Dr. Dario Vignali lab…

Congratulations to Khaled Sayed for the acceptance of his Scientific Reports paper, whichis entitled “The plasma degradome reflects later development of NASH fibrosis after liver transplant”. In this paper, Khaled helped analyze degradome and clinical data of patients undergone liver transplant in order to identify biomarkers for future development of liver…

Congratulations to Khaled Sayed and former Benos’ Lab member, Haopu Yang, for the acceptance of their iScience paper, whichis entitled “The upper and lower respiratory tract microbiome in severe aspiration pneumonia”.   In this paper, Khaled and Haopu helped analyze microbiome and clinical data of ICU patients to identify clusters with different…

Khaled Sayed accepted a full-time tenure-track appointment as Assistant Professor in the Department of Electrical and Computer Engineering & Computer Science, University of New Haven.  His position is starting on September 1, 2023.  Khaled has been a valuable member of our group since 2019.  He has worked…