All Posts

Congratulations to Tyler Lovelace for the acceptance of his first co-author BMC Medicine paper, which is entitled “Integrated unbiased multiomics defines disease-independent placental clusters in common obstetrical syndromes”. In this paper, Tyler analyzed placental-derived multi-comics datasets (mRNA, miRNA, proteins, metabolites) from pregnant women with different pregnancy abnormalities: preeclampsia, fetal growth restriction, spontaneous preterm…

Congratulations to Robert Gregg for the acceptance of his AJRCCM paper (“Blue journal”), which is entitled “Early Evidence of COPD Obscured by Race-Specific Prediction Equations”. This paper examines the impact of race-specific equations in the determination of the COPD disease status and severity. The main finding is that current race-specific equations underestimate the…

Congratulations to Minxue Jia for the acceptance of his first author Aging Cell paper, which is entitled “Transcriptional Changes of the Aging Lung”. In this paper, Minxue analyzed lung scRNA-seq data from carefully selected healthy donors across life span (19-78 yrs old). Some of the samples were the controls from existing publications, whereas…

Congratulations to Feng Shan for the acceptance of his first author Science Immunology paper, which is entitled “Integrated BATF transcriptional network regulates suppressive intratumoral regulatory T cells”. In this paper, Feng analyzes scRNA-seq data to uncover the transcriptional programs that control intratumoral Treg gene expression. This is a collaboration with Dr. Dario Vignali lab…

Congratulations to Khaled Sayed for the acceptance of his Scientific Reports paper, whichis entitled “The plasma degradome reflects later development of NASH fibrosis after liver transplant”. In this paper, Khaled helped analyze degradome and clinical data of patients undergone liver transplant in order to identify biomarkers for future development of liver…

Congratulations to Khaled Sayed and former Benos’ Lab member, Haopu Yang, for the acceptance of their iScience paper, whichis entitled “The upper and lower respiratory tract microbiome in severe aspiration pneumonia”.   In this paper, Khaled and Haopu helped analyze microbiome and clinical data of ICU patients to identify clusters with different…

Khaled Sayed accepted a full-time tenure-track appointment as Assistant Professor in the Department of Electrical and Computer Engineering & Computer Science, University of New Haven.  His position is starting on September 1, 2023.  Khaled has been a valuable member of our group since 2019.  He has worked…

Wenjie Zeng successfully passed her oral examination today at the Department of Epidemiology.  She did an excellent job answering all questions. She will now focus on completing her thesis work.  Congratulations Wenjie!   Untitled-768×363…

Daniel Yuan presented his work on single cell RNA-seq (scRNA-seq) analysis in cancer immunoprevention.  So far, MUC1 vaccine for colorectal cancer has induced strong immunogenicity in 25-43% of the participants. Analysis of blood scRNA-seq can help understand the mechanisms behind the responsiveness (or lack thereof) and build predictive models of response. Daniel…

Congratulations to Minxue Jia for the acceptance of his first author Respiratory Research paper, which is entitled “Early events marking lung fibroblast transition to profibrotic state in idiopathic pulmonary fibrosis”. In this paper, Minxue analyzed two publicly available scRNA-seq data from IPF patients and controls focusing on the transition of fibroblasts from normal to…