Takis participated in another study which investigated the role of mitochondria in cellular memory (transient or persistent) especially memory related to stress. The study was accepted for publication in Free Radical Biology & Medicine. Abstract (PubMed)…
Takis gave a talk at the plenary session on Artificial Intelligence (AI) at the annual Association for Molecular Pathology (AMP2018) meeting in San Antonio, Texas. He presented the work of the group on causal discovery from clinical and biomedical data. AMP2018 Program (Informatics): https://amp18.amp.org/program/program/informatics/…
Takis participated in a study which investigated how PACS-2 mediates SIRT1 activity by binding to a disordered region of the latter. SIRT1 is critical for DNA repair and metabolic fitness. The study was accepted for publication in Molecular Cell. Abstract (PubMed) UPDATE 2018-11-08: The paper is now available on…
The CausalMGM server is now live! People can learn causal structures from observational data using our software, by submitting jobs here (http://causalmgm.org). The web server was developed in collaboration with Prof. Chrysanthis group at CS@Pitt. The methodology is described in our recent Bioinformatics paper…
Vineet gave an excellent presentation at ECCB 2018 of the paper “piMGM: incorporating multi-source priors in mixed graphical models for learning disease networks”. The paper describes a method to evaluate edge priors and incorporate them in the structure learning of undirected graphs with mixed data. The paper…
AJ has another paper accepted for publication! This time in the journal Bioinformatics. This paper presents the CausalMGM method for learning directed graphs over mixed data types (continuous and discrete variables). The method is validated in both simulated and real data from patients.
Great news today. After many iterations, AJ’s paper was accepted for publication in the journal Neurosurgery. This paper presents the results of the analysis of gene, microRNA and protein expression from atherosclerotic carotid plaques in symptomatic and asymptomatic patients. Congratulations, AJ. UPDATE 2018-10-17: The paper is available from…
Takis was invited to give a seminar on causal modeling, as it applies to genetic analysis, in the Wellcome Advanced Summer Course “Genetic Analysis of Mendelian and Complex Diseases”. This gave him a nice opportunity to visit his old workplace (Wellcome Genome Campus at…
The paper of Vineet and Allen on “Evaluation of Causal Structure Learning Methods on Mixed Data Types” was accepted for oral presentation in the 2018 ACM SIGKDD Workshop on Causal Discovery. In this paper,…
Dimitris is a co-author in a paper entitled “Respiratory microbiome profiling for etiologic diagnosis of pneumonia in mechanically ventilated patients“, which was accepted in Frontiers in Microbiology. He used probabilistic graphical models to analyze microbiome data, protein biomarkers and clinical data to…
